Medication review

Sildenafil and tadalafil drug interactions

A safe ED assessment includes more than prescription medicines. Over-the-counter products, supplements and recreational substances can also affect risk.

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The direct answer

Nitrates and poppers are especially dangerous with common ED medications. Other medicines may require dose changes, monitoring or a different treatment plan.

Share the full list

Include medicines for chest pain, blood pressure, prostate symptoms, HIV, fungal infections and other conditions, along with supplements and recreational substances.

Do not change treatment on your own

Never stop a prescribed medicine to qualify for ED treatment. The clinician may coordinate with your regular prescriber or recommend another option.

Keep an up-to-date medication list

Keep a list with exact medication names and doses. If you are unsure, photograph the pharmacy labels or ask your pharmacist for a current profile.

Help for erection difficulties

ED symptoms and treatment options

Sildenafil and tadalafil help blood vessels relax, improving blood flow during sexual stimulation. That can make it easier to get and keep an erection firm enough for sex.

Trouble getting an erection?

Wanting sex but struggling to get firm enough can be a sign of ED. Find out how prescription treatment may help.

Difficulty getting an erection

Losing your erection during sex?

ED can also mean getting an erection but not keeping it. Learn about losing firmness and when medication may be an option.

Difficulty keeping an erection

Worrying about losing your erection?

Pressure to perform can make erection difficulties worse. Medication may help the erection response, but anxiety may also need separate support.

Performance anxiety and ED

Sexual stimulation is still needed. These medicines do not increase desire and are not suitable for everyone; a prescription is required.

When to seek medical advice

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Useful next steps

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